Genome annotation past, present, and future: How to define an ORF at each locus

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Figure 1.
Figure 1.

(A) A fragment of an alignment of a cDNA to genomic sequence containing 2 mismatches and a 15,907-bp intron. (B) Another alignment of the same two sequences containing no mismatches and a 5-bp exon in the intron of alignment A. All introns are bounded by canonical GT-AG splice sites.

This Article

  1. Genome Res. 15: 1777-1786

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