Comparing the human and chimpanzee genomes: Searching for needles in a haystack

Table 1.

Some phenotypic traits of humans for comparison with those of great apesa


LIFE HISTORY

ORGAN PHYSIOLOGY

NUTRITION

COGNITIVE CAPACITY
Secondary Altriciality Aldosterone Response to Posture Frugivory Declarative Memory
Helplessness of the Newborn Salt-Wasting Kidneys Carnivory Imitative Learning
Prolonged Helplessness of Young Ability For Sustained Running Aquatic Foods Teaching
Extended Care of Young Voluntary Control of Breathing Underground Foods Symbolic Representation
Childhood Ability to Dive Underwater Cooking Awareness of Death
Adolescence Diving Reflex Awareness of the Past
Age at First Reproduction Ability to Float/Swim NEUROANATOMY Awareness of the Future
Longevity Emotion Lacrimation Relative Brain Size Theory of Mind
Salt Content of Tears Direct Cortical Projections Theory of Other Minds
REPRODUCTIVITY BIOLOGY Olfactory Sense Relative Volume of Frontal Cortex Empathy
Concealed Ovulation Relative Volume of Corpus Callosum Numeracy
Virgin Breast Development CELL BIOLOGY Relative Volume of Cerebellum
Female Pituitary Menopause No Differences Are Known? % of Brain Growth Complete at Birth COMMUNICATION
Placentophagy Rate of Postnatal Brain Growth “Parentese” Sounds
Female Labia Majora BIOCHEMISTRY Infant “Protoconversations”
Vaginal Hymen Placental Alkaline Phosphatase NEUROBIOLOGY Gestural Communication
Baculum (Penis Bone) N-Glycolylneuraminic Acid Expression Population Distribution of Handedness Symbolic Communication
Sperm Count Alpha 2-6-Linked Sialic Acid Expression Semantics
Copulatory Plug Postnatal Dendritic Growth Grammar and Syntax
ENDOCRINOLOGY Postnatal Synapse Formation Recursion
EMBRYOLOGY Thyroid Hormone Metabolism Cortical Synapse Density Writing
Early Fetal Wastage/Aneuploidy Cortical Neuron Density
Hydatiform Molar Pregnancy PHARMACOLOGY Dendrites Per Neuron
Umbilical Cord Length Methylation of Inorganic Arsenic Synapses Per Neuron SOCIAL ORGANIZATION
Adult Neurogenesis Institutions
PREGNANCY/PARTURITION ANATOMIC PATHOLOGY Cingulate Cortical Spindle Neurons Social Conventions
Cephalo-pelvic Disproportion Cortical Neurofibrillary Tangles Finger Tip Sensory Nerve Endings Governments
Duration of Labor Enforcement Through Sanctions
Maternal Mortality in Childbirth CLINICAL PATHOLOGY NEUROCHEMISTRY
Pain During Childbirth Erythrocyte Sedimentation Rate Brain Aromatisation of Testosterone
Need for Assistance with Childbirth Serum Alkaline Phosphatase Level Tyrosine Hydroxylase Heterogeneity CULTURE
RBC and Serum Folate Composition of Art
Neonatal Cephalhematoma Serum Vitamin B12/B12 Binding MENTAL DISEASE Composition of Music
Total Leukocyte Count Schizophrenia Composition of Rhythms
POSTNATAL DEVELOPMENT Absolute Neutrophil Count Bipolar Psychosis Death Rituals
Late Closure of Cranial Sutures Absolute Lymphocyte Count Autism Clothing (Covering of Body Parts)
Duration of Infant Arousal Suicide
Inconsolable Infant Crying DENTAL BIOLOGY/DISEASE Rites of Passage
Infant-Caregiver Attunement Canine Tooth Diastema BEHAVIOR Genocide
Maternal-Infant Eye-To-Eye Gaze Canine Tooth Dysmorphism Control of Facial Expressions Competitive Sports
Tooth Enamel Thickness Planning Ahead Practicing of Skills
ANATOMY Retromolar Gap Intentional Deception Physical Modifications of the Body
Sagittal Crest of Skull Third Molar Impaction Deliberately Delaying Gratification
Brow Ridge Dental Eruption Sequence/Timing Long-Range Transport of Materials Inheritance of Resources and Status
Protuberantia Menti (Chin) Secondary Tool-Making
Length of Sphenoid Sinus MEDICAL/SURGICAL DISEASES Mechanical Multi-Tasking Rythmic Dance
Choroid Plexus Biondi Bodies HIV Progression to AIDS Physical Abuse of the Young Sculpture
Inner Ear Canal Orientation P. falciparum malaria Torture Belief in Supernatural/Religion
Apical Phalangeal Tufts Viral Hepatitis B/C Complications Organized Warfare
Age of Pelvic Bone Fusion Influenza A Infection Severity Adult Play Body Adornment
Bone Cortex Thickness Incidence of Carcinomas Symbolic Play Childbirth Customs
Laryngeal Position Hemorrhoids Abuse of Other Animals Sexual Intercourse in Private
Pharyngeal Air Sacs Varicose Veins Inter-Group Coalition Formation Gift-Giving
Ear Lobes Pelvic Phleboliths Use of Containers Hospitality
Sexual Body Size Dimorphism Foamy Virus (Spumavirus) Infections Care of Infirm and Elderly Intertwining (e.g., weaving)
Lacrimal Gland Structure Sexually Transmitted Diseases Grandparenting
Visible Whites of the Eyes Home Base Meal Times
Small/Large Intestine Length Ratio IMMUNOLOGY Control of Fire Poetry
Meningeal Artery Source Sialoadhesin on Macrophages Food Preparation Property
Organized Gathering of Food Construction of Shelters
BIOMECHANICS SKIN BIOLOGY AND DISEASE Domestication of Animals Taboos
Bipedal Gait Eyebrows Domestication of Plants Taxonomy of Species
Adductive Thumb Eccrine Sweat Glands Altruistic Punishment Trade
Skeletal Muscle Strength Acne Vulgaris Peace-Making Measurement of Time
Hand-Eye Coordination Subcutaneous Fat Somnambulism Weapons
Fine Motor Coordination
Body Lice
Mind-Altering Drug Use
Toys
  • a A major limitation in translating genomic comparative information into an understanding of “humanness” is that we know relatively little about the basic phenotypic features of the great apes, relative to humans. This table lists topic areas in which there are real or claimed “differences” between humans and the great apes (as a group). A given “difference” listed here could be a suggested gain or loss in humans, with respect to the great apes. This is a partial listing of topics that will appear later at a Web-based “Museum of Comparative Anthropogeny” http://origins.ucsd.edu/gapp1.html

This Article

  1. Genome Res. 15: 1746-1758

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