Table 1.
Parameters of best-fitting model
|
Variable parameters |
Best-fit model |
| Ne (ancestral) | 12,500 |
| Ne (African) | 24,000 |
| Ne (non-African) | 7700 |
| T (African expansion) (gens) | 17,000 |
| OoA bottleneck (F) | 0.085 |
| Asian bottleneck (F) | 0.067 |
| European bottleneck (F) | 0.020 |
| African bottleneck (F) | 0.008 |
| Africa ↔ Europe migration rate (per chromosome) | 3.2 × 10-5 |
| Africa ↔ Asia migration rate (per chromosome) | 0.8 × 10-5 |
| Recombination hotspot spacing (bp) | 8500 |
| Hotspot spacing shape parameter | 0.35 |
| Fraction of recombination in hotspots | 88% |
| Gene conversion (initiation prob/bp) | 4.5 × 10-9 |
| Fixed parameters
|
|
| Mutation rate (per base pair per generation) | 1.5 × 10-8 |
| Ne (post-agriculture) | 100,000 |
| T (out of Africa) (gens) | 3500 |
| T (Eur/Asia split) (gens) | 2000 |
| T (Asian agriculture) (gens) | 400 |
| T (European agriculture) (gens) | 350 |
| T (African agriculture) (gens)
|
200
|
