Genomic regions exhibiting positive selection identified from dense genotype data

Table 2.

Regions selected for targeted resequencing







Tajima's D

θd (× 10-4)

Πe(× 10-4)
Region
Genome coordinatesa
Popb
Gene
bpc
AD
ED
XD
AD
ED
XD
AD
ED
XD
1 Chr1: 35,270,001-36,160,000 ED CLSPN 16308 -1.29 -2.44f -1.07 5.25 2.49 2.07 3.26 0.57 1.35
2 Chr1: 41,130,001-41,420,000 AD CTPS 26417 -0.90 0.15 -0.05 7.08 6.06 5.71 5.29 6.30 5.63
2 Chr1: 41,130,001-41,420,000 AD FLJ23878 7266 -1.66 0.62 -0.11 7.75 7.13 5.89 3.85 8.48 5.69
2 Chr1: 41,130,001-41,420,000 AD SCMH1 30057 -2.00 -0.49 -0.85 7.87 6.30 5.92 3.47 5.44 4.51
3 Chr2: 108,400,001-109,070,000 XD EDAR 22094 -0.46 -2.06 -2.40 13.26 9.48 3.06 11.58 4.02 0.87
4 Chr2: 162,870,001-163,190,000 ED GCG 13293 -0.46 -1.77 -0.96 6.27 4.07 5.59 5.43 1.88 4.00
5 Chr11: 37,820,001-38,290,000 XD BX115137 6422 -0.01 0.77 -2.60 13.68 9.12 7.37 13.65 11.24 1.43
6
Chr4: 32,930,000-33,560,000
ED
AW183861
21630
-1.28
-1.92
-2.07
5.73
2.60
1.88
3.63
1.08
0.65
  • a May 2004 build, hg17.

  • b Population with observed CRTR.

  • c Base pairs resequenced.

  • d Watterson's nucleotide diversity per base pair estimated from the number of segregating sites.

  • e Kimura's nucleotide diversity per base pair estimated from the average heterozygosity per site.

  • f Values of Tajima's D less than -2, the theoretical 95% lower bound for Tajima's D are shown in bold.

This Article

  1. Genome Res. 15: 1553-1565

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