Table 3.
Estimation of population crossing-over and gene conversion rates
|
|
|
A. Whole LHB/CGB region |
B. Recombination hotspot |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Estonians |
Han |
Mandenka |
Estonians |
||||||||||||
|
|
|
All SNPs |
≥10% MAFd |
All SNPs |
≥10% MAF |
All SNPs |
≥10% MAF |
All SNPs |
>10% MAF |
||||||
| Maximum PAC likelihood estimates (Li and Stephens 2003) | |||||||||||||||
| ρa (× 104) | 4.16 | 4.43 | 2.91 | 2.34 | 17.00 | 8.93 | 43.21 | 35.91 | |||||||
| Composite likelihood estimates (Frisse et al. 2001; Hudson 2001) | |||||||||||||||
| L = 0b | ρ (× 104) | 8.02 | 7.40 | 7.21 | 7.06 | 17.63 | 14.92 | 93.42 | 68.05 | ||||||
| L = 30 | ρ (× 104) | 6.38 | 6.25 | 6.60 | 6.53 | 12.29 | 10.38 | 68.05 | 56.17 | ||||||
| fc | 14 | 12.5 | 6 | 6 | 13 | 16 | 3 | 2 | |||||||
| L = 50 | ρ (× 104) | 6.36 | 6.21 | 6.55 | 6.53 | 12.29 | 10.32 | 67.36 | 54.63 | ||||||
| f | 9 | 8 | 4 | 3.5 | 8 | 10 | 2 | 1.5 | |||||||
| L = 100 | ρ (× 104) | 6.41 | 6.23 | 6.55 | 6.49 | 12.12 | 10.17 | 57.96 | 52.83 | ||||||
| f | 4.5 | 4 | 2 | 2 | 4.5 | 5.5 | 2 | 1 | |||||||
| L = 250 | ρ (× 104) | 6.41 | 6.13 | 6.82 | 6.68 | 12.18 | 10.11 | 35.96 | 34.58 | ||||||
| f | 2 | 0.5 | 0.5 | 2.5 | 2 | 2.5 | 3 | 2 | |||||||
| L = 500 | ρ (× 104) | 6.49 | 6.20 | 6.49 | 6.42 | 11.80 | 10.25 | 16.11 | 17.74 | ||||||
|
|
f
|
1
|
1
|
0.5
|
0.5
|
1
|
1.5
|
6.5
|
4
|
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