Table 2.
Minimal gene conversion (GC) tracts identified within LHB/CGB genes and potential donor genes of a converted segment
|
Acceptor GC site |
Potential donor gene |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene |
No. |
LHB |
CGB |
CGB2 |
CGB1 |
CGB5 |
CGB7 |
CGB8a |
|||||||
| LHB | 1 | +122; +125 | +122; +125 | +122; +125 | +122; +125 | +122; +125 | +122; +125 | ||||||||
| +122; +154 | |||||||||||||||
| 2 | +466; +546 | +466; +546 | +466; +546 | +466; +546 | +466; +546 | +466; +546 | |||||||||
| +484; +546 | +484; +546 | +484; +546 | +484; +546 | +484; +546 | +484; +546 | ||||||||||
| CGB | 1 | -328; -268 | |||||||||||||
| 2 | -185; -180 | -185; -180 | -185; -180 | ||||||||||||
| -185; -144 | |||||||||||||||
| 3 | -111; -109 | -111; -109 | |||||||||||||
| 4 | -77; -76 | -77; -76 | |||||||||||||
| 5 | +88; +101 | +88; +101 | +88; +101 | +88; +101 | +88; +101 | ||||||||||
| 6 | +126; +168 | +155; +168 | +155; +168 | ||||||||||||
| +163; +168 | +163; +168 | +163; +168 | +163; +168 | ||||||||||||
| 7 | +554; +674 | ||||||||||||||
| 8 | +751; +1137 | +751; +1026 | |||||||||||||
| +1026; +1038 | +1026; +1137 | +1026; +1038 | |||||||||||||
| +1038; +1109 | |||||||||||||||
| CGB2 | 1 | +353; +354 | +353; +354 | +353; +354 | +353; +354 | +353; +354 | +353; +354 | ||||||||
| 2 | +507; +531 | +507; +531 | |||||||||||||
| CGB1 | 1 | +219; +241 | |||||||||||||
| 2 | +452; +458 | +452; +458 | +452; +458 | +452; +458 | +452; +458 | +452; +458 | |||||||||
| 3 | +794; +1150 | +1087; +1150 | |||||||||||||
| +1136; +1150 | +1136; +1150 | +1136; +1150 | +1136; +1150 | ||||||||||||
| CGB5 | 1 | No GC tracts identified | +151; +160 | ||||||||||||
| 2 | +179; +186 | +179; +186 | |||||||||||||
| 3 | +673; +704 | +673; +704 | +673; +704 | +673; +704 | |||||||||||
| CGB7 | 1 | -394; -396 | -394; -396 | ||||||||||||
| 2 | -379; -357 | ||||||||||||||
| 3 | -58; -46 | -58; -46 | -58; -46 | ||||||||||||
| -58; +60 | |||||||||||||||
| 4 | +198; +200 | +198; +301 | +198; +200 | +198; +200 | +198; +301 | ||||||||||
| +298; +301 | +298; +301 | +298; +299 | |||||||||||||
| 5 | +422; +423 | +422; +423 | +417; +423 | +417; +423 | +417; +423 | +422; +423 | |||||||||
| +417; +553 | +417; +553 | ||||||||||||||
| 6 | +1061; +1151 | ||||||||||||||
| 7 | +1241; +1278 | ||||||||||||||
| CGB8a | 1 | No GC tracts identified | No GC tracts identified | No GC tracts identified | -268; -265 | ||||||||||
|
|
2
|
|
|
+1146; +1147
|
+1146; +1147
|
|
|
|
|||||||
-
Exact position of GC site (beginning; end) is defined by its localization in acceptor gene relative to ATG. Distribution of GC acceptor sites relative to exon—intron structure of the genes is presented in Figure 2.
-
↵a CGB8 data are from the analysis of 11 Estonian individuals; the analysis of the rest of the genes is based on the combined sample set of 95 Estonian, Han, and Mandenka individuals.
