Table 7.

Relationship between hotspots for the rapid breakdown of linkage disequilibrium and chromosomal organization

	CEU sample			YRI sample
	Hotspots	Other intervals	Hotspots	Other intervals	Hotspots	Other intervals
Number of intervals	14,525	702,099	15,623	750,857	12,607	610,826
Chromosome organization
Within 5 Mb of centromere	325	471**	324	460**	282	464**
Within 10 Mb of centromere	965	1124**	942	1127**	933	1115**
Within 15 Mb of centromere	1715	1804	1647	1816**	1685	1798*
Within 5 Mb of telomere	795	352**	879	336**	766	347**
Within 10 Mb of telomere	1642	773**	1793	746**	1635	765**
Within 15 Mb of telomere	2219	1179**	2425	1138**	2273	1170**
Within 5 Mb of heterochromatin	195	271**	202	273**	182	269**
Within 10 Mb of heterochromatin	553	694**	575	700**	558	700**
Within 15 Mb of heterochromatin	1057	1153*	1041	1159*	1077	1160
Large genomic duplications	85	137**	107	133*	78	129**
Large genomic duplications (cis)	41	81**	53	78*	43	75**
Large genomic duplications (trans)	47	67*	62	65	40	62*

Sequence features in regions of weak and strong linkage disequilibrium