Sequence features in regions of weak and strong linkage disequilibrium

Table 2.

Correlation between chromosomal organization and linkage disequilibrium in windows of 100, 500, and 1000 kb



CEU sample

YRI sample

CHB+JPT sample
Chromosome organization
100 kb
500 kb
1000 kb
100 kb
500 kb
1000 kb
100 kb
500 kb
1000 kb
Within 5 Mb of centromere 0.13* 0.16* 0.17* 0.13* 0.17* 0.19* 0.12* 0.15* 0.17*
Within 10 Mb of centromere 0.10* 0.12* 0.14* 0.11* 0.14* 0.16* 0.09* 0.11* 0.13*
Within 15 Mb of centromere 0.08* 0.10* 0.12* 0.09* 0.12* 0.14* 0.07* 0.09* 0.11*
Within 5 Mb of telomere -0.15* -0.19* -0.21* -0.14* -0.18* -0.21* -0.14* -0.17* -0.20*
Within 10 Mb of telomere -0.21* -0.26* -0.29* -0.20* -0.26* -0.29* -0.19* -0.25* -0.27*
Within 15 Mb of telomere -0.23* -0.29* -0.32* -0.22* -0.28* -0.32* -0.22* -0.27* -0.31*
Within 5 Mb of heterochromatin 0.09* 0.11* 0.12* 0.09* 0.12* 0.14* 0.09* 0.11* 0.13*
Within 10 Mb of heterochromatin 0.08* 0.09* 0.11* 0.08* 0.10* 0.13* 0.08* 0.10* 0.12*
Within 15 Mb of heterochromatin 0.05* 0.06* 0.07* 0.06* 0.08* 0.10* 0.05* 0.06* 0.08*
Large genomic duplications 0.07* 0.07* 0.06* 0.07* 0.06* 0.05 0.07* 0.07* 0.06*
Large genomic duplications (cis) 0.05* 0.04* 0.03 0.06* 0.03 0.01 0.04* 0.03 0.02
Large genomic duplications (trans)
0.06*
0.10*
0.09*
0.07*
0.09*
0.09*
0.07*
0.10*
0.10*
  • * Correlation is significant at P < 0.0001 level

This Article

  1. Genome Res. 15: 1519-1534

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