Table 1.
Previously unidentified ohnolog pairs in S. cerevisiae
|
Gene 1 |
Gene 2 |
Syntenic support |
BLASTP E-value |
|---|---|---|---|
| SPO21 (YOL091W) | YSW1 (YBR148W) | Pre-WGD | >1a |
| YJR039W | YEL025C | Pre-WGD | >1a |
| ORC4 (YPR162C) | RIF2 (YLR453C) | Pre-WGD | >1a |
| YNL195C | HBT1 (YDL223C) | Pre-WGD | >1a |
| REG1 (YDR028C) | REG2 (YBR050C) | Pre-WGD | 6.2 |
| STB1 (YNL309W) | YOL131W | Pre-WGD | 0.67 |
| SIP18 (YMR175W) | GRE1 (YPL223C) | Pre-WGD | 0.05 |
| SPO19 (YPL130W) | YOR214C | Post-WGD | 0.027 |
| YFR017C | YOL024W | Pre-WGD | 0.008 |
| YGR035C | YLR346C | Post-WGD | 0.002 |
| ECM13 (YBL043W) | YJR115W | Pre-WGD | 2.00E-06 |
| PEX25 (YPL112C) | PEX27 (YOR193W) | Pre-WGD | 1.00E-08 |
| YAP5 (YIR018W) | YAP7 (YOL028C) | Post-WGD | 6.00E-14 |
| ASI1 (YMR119W) | ASI3 (YNL008C) | Inferredb | 4.00E-24 |
| YJL181W | YJR030C | Inferredb | 2.00E-31 |
| YEL007W | YHR177W | Inferredb | 4.00E-38 |
| HYR1 (YIR037W) | GPX1 (YKL026C) | Post-WGD | 6.00E-55 |
| SNO3 (YFL060C) | SNO2 (YNL334C) | Pre-WGD | 1.00E-117 |
| YFR022W | ROD1 (YOR018W) | Inferredb | 1.00E-118 |
| SAM4 (YPL273W) | MHT1 (YLL062C) | Post-WGD | 1.00E-124 |
| SNZ3 (YFL059W) | SNZ2 (YNL333W) | Pre-WGD | 1.00E-159 |
| MMP1 (YLL061W)
|
SAM3 (YPL274W)
|
Post-WGD
|
0
|
-
↵a Sequences do not hit each other in a BLASTP search, but there is indirect BLASTP support for these ohnologs via a mutual homolog
-
↵b There is no direct syntenic support to suggest that these S. cerevisiae gene pairs are ohnologs, but a combination of some or all of the following convinces us they are ohnologs: synteny in the other post-WGD and pre-WGD genomes at that locus, two copies of the gene in other post-WGD genomes, correct clading in phylogenetic trees, or similar protein lengths
