Evolutionary constraints in conserved nongenic sequences of mammals

Table 1.

Numbers of nucleotide differences and nucleotide divergences in CNGs and their flanking DNA segments of up to 10 kb at non-CpG-prone sites


Species pair

DNA category

Sites

Differences

Proportion of differences (SE)

Evolutionary rate (SE)
Human-chimp CNG 215,888 1859 0.00862 (0.00021) 0.00866 (0.00022)
CNG 5′-flank 5,350,833 64,995 0.0121 (0.00010) 0.0123 (0.00009)
CNG 3′-flank 5,269,495 63,740 0.0121 (0.00012) 0.0122 (0.00010)
Mouse-rat CNG 188,225 13,342 0.0709 (0.00098) 0.0747 (0.00108)
CNG 5′-flank 2,446,742 361,742 0.148 (0.00057) 0.167 (0.00074)

CNG 3′-flank
2,341,277
345,408
0.148 (0.00047)
0.167 (0.00076)

This Article

  1. Genome Res. 15: 1373-1378

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