Table 1.
Evaluation of synteny-based feature tracking between pairs of orthologous mouse and rat sequences
|
Orthologs class |
mRNA pairs/exons |
Exon W = 0/5/10 bp |
Splice site W = 0/5/10 bp |
Base-pair |
|---|---|---|---|---|
| Exact | 1,842/14,460 | Sn: 0.96/0.97/0.97 | Sn: 0.97/0.98/0.98 | Sn: 0.97 |
| Sp: 0.98/0.99/0.99 | Sp: 0.99/1.00/1.00 | Sp: 1.00 | ||
| Near-exact | 282/1,872 | Sn: 0.91/0.93/0.93 | Sn: 0.92/0.92/0.93 | Sn: 0.92 |
|
|
|
Sp: 0.93/0.95/0.96
|
Sp: 0.94/0.95/0.96
|
Sp: 0.95
|
-
Sensitivity (Sn) and specificity (Sp) values at exon, splice site, and base-pair levels were measured as described in Burset and Guigo (1996). Exon and splice site statistics were computed allowing for a variable window of W = 0, 5, and 10 bp. “Exact” orthologs have all orthologous exons exactly matching when projected via the cDNA–cDNA alignment (see Methods). “Near-exact” pairs have orthologous mouse and rat exon ends matching within 10 bp.
