Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates

Table 1.

Domain and full-length nucleotide comparisons between the chimpanzee and macaque novel genes with previously identified cDNAs and KIR2DP1



Closest sequences (number of differences)

Full-length
D0
D1
D2
S/TM/CYT
ptKIRnewI ptKIRCI (23) ptKIRCI (1) ptKIRCI (1) ptKIRCI (0) KIR2DPI (12)
ptKIRCI (13)
ptKIRnewII ptKIR2DL6 (23) ptKIR2DL6 (1) ptKIR3DL6 (1) ptKIR3DL6 (0) ptKIR2DL3 (13)
ptKIR2DL6 (2) ptKIR2DL6 (0) ptKIR2DL6 (20)
ptKIRnewIII ptKIR2DL6 (39) ptKIR2DL6 (4) ptKIR3DL6 (10) ptKIR3DL7 (9) ptKIR3DL4 (10)
ptKIR3DL7 (10) ptKIR2DL6 (9) ptKIR2DL6 (15)
ptKIR2DL6 (11)
mmKIRnewI
mmKIR2DL5.1 (3)
mmKIR2DL5.1 (0)
ggKIR3DL3 (25)
mmKIR2DL5.1 (3)
mmKIR2DL5.1 (0)
  • Domains have been divided into Ig D0, Ig D1, Ig D2 and the combined sequence of the stem, transmembrane, and cytoplasmic tail (S/TM/CYT).

This Article

  1. Genome Res. 15: 25-35

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