Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates

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Figure 4.Figure 4.
Figure 4.

Phylogenetic analysis of the KIR genes carried out on a domain-by-domain basis, including Ig D0 (A), Ig D1 (B), Ig D2 (C), and the combined stem, transmembrane, and cytoplasmic tail (D). The tree has been constructed using the Neighbor Joining (NJ) method. Novel genes identified in the common chimpanzee and rhesus macaque haplotypes analyzed are shown in bold. Sequences have been grouped into five lineages (I, II, III, IV, V) and are enclosed within boxes. The previously identified ptKIR3DL3 cDNA does not correspond to the human KIR3DL3 gene but rather is allelic to ptKIR3DL1/2.

This Article

  1. Genome Res. 15: 25-35

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