Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates

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Figure 3.
Figure 3.

Multiple sequence alignment of the novel mmKIRnewI gene in the rhesus macaque (shown in bold). Periods (.) indicate identity with mmKIRnewI and dashes (-) indicate the absence of amino acids. Human KIR2DL4 and KIR2DL5 genes have the D0+D2 structure. Conserved cysteine residues in the immunoglobulin domains are highlighted. ITIM motifs are shown by asterisks. The cDNA sequences are available under accession numbers AAK26807 (mmKIR2DL5.1) and AAK26808 (mmKIR2DL5.2).

This Article

  1. Genome Res. 15: 25-35

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