Mulan: Multiple-sequence local alignment and visualization for studying function and evolution

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

Stacked-pairwise conservation profile for a 13-kb region from the GATA3 locus. Color-gradient visualization is implemented to differentially display regions that are differentially conserved in the input sequences (A). The color intensity of a conserved region depends on the number of different species that contain the region (the darker, the more conserved species). Only ECRs conserved in at least six out of seven total secondary species are highlighted in the alignment (B). Intergenic regions are in red, intronic in pink, coding exons in blue, and UTRs in yellow.

This Article

  1. Genome Res. 15: 184-194

Preprint Server