Evolution of the Beckwith-Wiedemann syndrome region in vertebrates

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Figure 1.
Figure 1.

Schematic map of orthologous genes in different species. Shown are maps of the human, chicken, zebrafish, and Fugu gene syntenies across the BWS region. The map is not to scale. Black bars indicate regions that are spanned by assembled genomic shotgun sequences and by BAC clones. For the remaining regions only shotgun assembled sequences were available. Interruptions of the horizontal lines indicate long distances between the genes. The chicken BWS region is present on two BAC contigs (contig 1: GenBank accession nos. BX640540, BX640401, contig 2: GenBank accession nos. BX649221, BX649222, BX640404, AP003796, AP003795, BX663531). The sequence contig in zebrafish is derived from five BAC sequences (GenBank accession nos. AL928843, AL929208, AL928880, BX001047, AL928628). The Fugu Igf2, Th, and Nap1l4 genes were also found in a cosmid sequence (GenBank accession no. AL021880).

This Article

  1. Genome Res. 15: 146-153

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