Widespread RNA Editing of Embedded Alu Elements in the Human Transcriptome

Table 1.

Distribution of A-to-G Substitutions Within 2674 Selected Transcripts


Repeat element-type

No. of repeat elements

Total bases (% of total)

A-to-G substitutions (% of total)

Distribution of A-to-G substitutions in repeat elements (minimum, 25th percentile, median, 75th percentile, maximum)

Other 11 substitutions combined (% of total)
Alu 6763 1,570,185 (20.7%) 30,744 (87.6%) 0,0,4,7,34 2017 (26.4%)
Other repeatsa 6840b 1,472,934 (19.4%) 1826 (5.2%) 0,0,0,0,63 1396 (18.3%)
Non-repeatsc 4,555,872 (59.9%) 2515 (7.2%) 4235 (55.4%)
Total
13603b
7,598,991
35,085

6763
  • a Other repeats include, but are not limited to LINE-1, LTR, and DNA transposon families.

  • b Owing to the often interrupted structure of non-Alu repeats, this number is likely to be an overestimate.

  • c Non-repeats refer to sequences other than interspersed complex repeats and include unique sequences as well as low complexity repeats and satellites.

This Article

  1. Genome Res. 14: 1719-1725

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