Large-Scale Validation of Single Nucleotide Polymorphisms in Gene Regions

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Figure 2
Figure 2

Correlation between frequencies from this study and matched Caucasian TSC SNP allele frequencies. The relationship between allele frequencies for 5,644 SNPs measured in the current study (SQNM CEPH) and matched Caucasian frequencies in the TSC collection (TSC CAUC) is compared with a bivariate contour plot. Density lines are plotted every 0.5 units, ranging from 0.5 for the outermost line to the highest density of 3.0 for the innermost line. The allele presented was arbitrarily standardized to the MassEXTEND high mass allele from each assay in this study. SNPs with minor allele frequencies <0.05 in both SQNM CEPH and TSC CAUC samples were excluded from this plot. Lower frequency SNPs are compared at the bottom of Table 1.

This Article

  1. Genome Res. 14: 1664-1668

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