Early Genetic Mechanisms Underlying the Inhibitory Effects of Endostatin and Fumagillin on Human Endothelial Cells

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Figure 3
Figure 3

Gene expression profile for DOC1, KLF4, ID1, and TC1 over the time course of treatment with 10 μg/mL endostatin (A) and 10 nM fumagillin (B). Of the list of genes with twofold up- or down-regulation in at least one time point, we chose these four genes because they have the same time course of expression in response to the two inhibitors we used. The y-axis represents the ratio between treated and nontreated cells (Cy5 intensity value for treated over Cy3 intensity value for untreated).

This Article

  1. Genome Res. 14: 1585-1593

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