Figure 2
Microarray cluster image of the gene expression profile of HUVEC treated with 10 μg/mL endostatin (A) and 10 nM fumagillin (B) over the time course of 0 h, 30 min, 1, 2, 4, and 8 h. The cluster is ordered by genes, and shows a list of genes that are up- or down-regulated by twofold for at least one time point. The majority of gene expression changes appeared to occur for both agents within 1 and 2 h of treatment. With Cy5, we labeled the mRNA from treated cells, and with Cy3, the mRNA from nontreated cells.
