Clustering of DNA Sequences in Human Promoters

To the left are the eight consensus sequences followed by the number of their occurrences in the peak, and the percentage of promoters containing this sequence. Across the top is the same set of consensus sequences. The intersection is the number of promoters containing both sequences in the peak, followed by the percentage of the promoters containing the top sequence that also contain the sequence from the side, and the probability of having the number of elements in the intersection more dramatic than given. For example, 20.7% of the 13,010 promoters contain the SP1 sequence in the peak (2696), but 33.5% of promoters that contain a USF sequence (191) in the peak also contain the SP1 sequence in the peak. The probability of this positive correlation between these two DNA sequences is P = 4.7. Those correlations that are greater than P = 5 are shown in black, a positive correlation has an asterisk in the probability column.