Regional Patterns of Gene Expression in Human and Chimpanzee Brains

Table 4.

Distribution of Gene Expression Differences Between Humans and Chimpanzees Across the Human Genome


Changed genes

Number of windows

Observed
Simulated mean
p-value
0/21 1024 705 <0.0001
1/21 2561 2241 0.0006
2/21 3195 3380 0.9385
3/21 2812 3219 0.9997
4/21 2000 2172 0.9720
5/21 900 1104 0.9997
6/21 493 439 0.1085
7/21 263 140 <0.0001
8/21 108 36 <0.0001
9/21 41 8 0.0002
10/21 23 1 0.0000
11/21 9 0 0.0009
12/21 6 0 0.0005
13/21 5 0 0.0001
14/21 2 0 <0.0001
15/21 2 0 <0.0001
16/21
1
0
<0.0001
  • The numbers of 21-gene-windows showing different numbers of differently expressed genes are given for the observed data as well as for the mean of 1.5 million permutated data sets. Significant differences (p < 0.05) between the observed and the simulated random data are indicated by italicized p-values.

This Article

  1. Genome Res. 14: 1462-1473

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