Number of genes exhibiting expression patterns specific to brain regions in humans and chimpanzees. (A) Genes with region-specific expression among the cerebral cortex (CX), the caudate nucleus (CN), and cerebellum (CB). Genes with expression specific for the cerebral cortex were defined as not showing any significant difference among the four cerebral cortex regions but significant differences to both the caudate nucleus and the cerebellum in at least one of these four regions. The numbers of genes with correlation coefficients <0.6 between human and chimpanzee brain expression profiles are shown in parentheses. (B) Genes with region-specific expression among four brain regions in a broader analysis of the transcriptome including the anterior cingulate cortex (ACC) and Broca's area (B).
