Two Breakpoint Clusters at Fragile Site FRA3B Form Phased Nucleosomes

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1
Figure 1

Genomic organization of the FHIT/FRA3B region. The FHIT sequence is shown from intron 3 through intron 6. The position of the unstable FRA3B region is indicated by a hatched bar. The major breakpoint clusters are marked by black blast symbols within the 2150-bp EcoRI fragment of the proximal region and the 1899-bp AflIII fragment of the distal region. Solid circles represent the locations of Alu elements. (E) EcoRI; (A) AflIII.

This Article

  1. Genome Res. 14: 1350-1357

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research