Figure 8
Mechanisms of intron loss. (A) Loss by recombination with cDNA. In the genomic DNA, coding sequences are shown as gray boxes. Sites of recombination are marked with an X. (B) Loss by deletion. Only one of several possible mechanisms for deletion is shown. (C) Loss by mutation of the donor site. (*) The site of a point mutation that destroys the donor site. The dark gray box indicates in-frame intron sequences that have become part of the coding sequence.
