Genomics, Prior Probability, and Statistical Tests of Multiple Hypotheses

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1
Figure 1

Posterior error rate for an experiment in which the null hypothesis is rejected, as a function of the ratio of π1 to significance level α, for β = 0.2, and two significance levels as shown. As discussed in the text, π1 is the fraction of tests in a family for which the null hypothesis is actually false. The arrow shows the approximate minimum ratio to achieve a PER of no more than 0.2.

This Article

  1. Genome Res. 14: 997-1001

Preprint Server