Differential Alu Mobilization and Polymorphism Among the Human and Chimpanzee Lineages

Table 1.

Lineage-specific Alu Insertions




Human

Human/Chimp ratio

Chimpanzee
Observed inserted total 101 2.20 46
PCR tested 78 43
Fixed present 63 26
Observed polymorphic 16 18
Observed polymorphic fraction 0.21 0.50 0.41
Adjusted polymorphica 31-33 35-37
Adjusted polymorphic fraction 0.33-0.34 0.56-0.60 0.57-0.59
Adjusted inserted total
116-118
1.84-1.93
61-63
  • a Adjusted polymorphic fraction was calculated based upon simulation of the frequency of polymorphic Alu elements observed in a given genome by sampling alleles from a uniform frequency distribution (see Methods). Ranges indicated were generated based on 95% confidence intervals derived by simulation.

This Article

  1. Genome Res. 14: 1068-1075

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