Table 1.

Plasmodium Subtelomeric Multigene Family Encoding 2-Transmembrane Proteins: Structural Properties

Name^a	Locus^b	Chr^c	Loc^d	Exons	SubC^e	Length	MW	pI	SP^f	TM^g	S1^g	E1^g	S2^g	SE2^g	Loop^h
PfMC-2TM_1.2	PFA0680c*	1	ST	2	MC	229	26899.8	9.69	1	2	157	179	184	203	4
PfMC-2TM_1.1	PFA0065w*	1	ST	2	MC	234	27446.4	9.66	1	2	160	182	186	208	3
PfMC-2TM_2.2	PFB0985c	2	ST	2	MC	229	27063.0	9.57	1	2	156	178	182	204	3
PfMC-2TM_2.1	PFB0960c*	2	ST	2	MC	225	26752.6	9.52	1	2	157	179	184	203	4
PfMC-2TM_3	PFC1080c	3	ST	2	MC	231	27004.6	9.47	1	2	162	184	189	208	4
PfMC-2TM_6	MAL6P1.15*	6	ST	2	MC	231	27183.1	9.60	1	2	157	179	183	205	3
PfMC-2TM_7.1	MAL7P1.5	7	ST	2	MC	235	27557.2	9.57	1	2	162	184	188	210	3
PfMC-2TM_7.2	MAL7P1.58	7		2		231	27329.0	9.55	1	2	159	181	186	208	4
PfMC-2TM_10	PF10_0390*	10	ST	2	MC	230	27217.9	9.55	1	2	153	175	185	204	9
PfMC-2TM_11.2	PF11_0025	11	ST	2	MC	231	27194.1	9.57	1	2	157	179	184	206	4
PfMC-2TM_11.1	PF11_0014*	11	ST	2	MC	231	27179.8	9.29	1	2	162	184	189	208	4

Protein names ^a are proposed based on known subcellular localization ^e. Genes ^b, which were modified from their published annotation (Gardner et al. 2002), are marked with an asterisk. The gene locations within chromosomes ^c are reported in ^d. The presence of a signal peptide (SP)^f, as predicted by SignalP (Nielsen et al. 1997), and the number of transmembrane domains (TM)^g, as predicted by TMHMM (Krogh et al. 2001) are reported, as well as the position of these TM segments within the protein sequence^g and the number of amino acid residues separating the two TMs^h.

A Plasmodium Gene Family Encoding Maurer's Cleft Membrane Proteins: Structural Properties and Expression Profiling