The Small Chromosomes of Trypanosoma brucei Involved in Antigenic Variation Are Constructed Around Repetitive Palindromes

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Figure 6
Figure 6

A model for the generation of palindromic MCs from larger chromosomes containing inverted repeats. Extrusion of inverted repeats into a cruciform structure induces a chromosome double-strand break. Interstrand ligation creates a hairpin that becomes a large palindrome upon DNA replication.

This Article

  1. Genome Res. 14: 1014-1024

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