The Small Chromosomes of Trypanosoma brucei Involved in Antigenic Variation Are Constructed Around Repetitive Palindromes

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Figure 1
Figure 1

The karyotype of Trypanosoma brucei as assessed by pulsed-field gel electrophoresis of whole-chromosome-sized DNAs. The chromosomes fall into three classes: megabase-sized chromosomes (MBCs), intermediate-sized chromosomes (ICs), and minichromosomes (MCs). ICs and MCs contain large quantities of a 177-bp satellite repeat sequence, as shown by hybridization to labeled repeat (177). This repeat is also found on a circular extrachromosomal element of ∼70 kb, which runs aberrantly on pulsed-field gels (star).

This Article

  1. Genome Res. 14: 1014-1024

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