Effect of Expression Breadth on Significance of Local Similarity in KA (Duplicate Genes Excluded)
|
|
Human—mouse |
Mouse—rat |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Breadth measurea |
ρ |
Pallb |
Pgroupc |
N |
ρ |
Pallb |
Pgroupc |
N |
||||||
| EST | 0.047 | 0.0072 | 0.016 | 3115 | 0.023 | 0.10 | 0.069 | 3029 | ||||||
| SAGE | 0.041 | 0.032 | 0.044 | 2572 | 0.041 | 0.024 | 0.020 | 2740 | ||||||
| Microarray
|
-0.037
|
0.90
|
0.92
|
1209
|
0.038
|
0.071
|
0.049
|
1559
|
||||||
-
↵a Breadth of expression was averaged over experiments in human and mouse for the human—mouse comparison, and was obtained from mouse only in the mouse—rat comparison.
-
↵b Pall is the number of equal or greater ρ in datasets obtained by randomly permuting all genes.
-
↵c Pgroup is the number of equal or greater ρ in datasets obtained by randomly permuting genes within classes of similar expression breadth.











