Genomic Regionality in Rates of Evolution Is Not Explained by Clustering of Genes of Comparable Expression Profile

Table 6.

Local Similarity in Nonsynonymous Substitution Rate KA, Including All Genes or Excluding Duplicate Genes



Human—mouse

Mouse—rat

ρ
P
N
ρ
P
N
All genes 0.126 <0.0001 4596 0.055 0.0018 4116
Nonduplicatesa
0.065
0.0002
4515
0.022
0.087
3995
  • a Genes were excluded from the focal average if they exhibited significant sequence similarity to the focal gene (BLAST expectation value E <0.02; Lercher et al. 2001).

This Article

  1. Genome Res. 14: 1002-1013

Preprint Server