Computational Analysis of Plasmodium falciparum Metabolism: Organizing Genomic Information to Facilitate Drug Discovery

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Figure 4
Figure 4

The thick arrows represent reactions that are catalyzed by enzymes, whereas the thin arrows represent reactions that are present, but with no evidence of the corresponding enzymes. When determining chokepoint reactions, we only consider the catalyzed reaction. (1) A chokepoint, because it produces a unique product; (2) a chokepoint, because it consumes a unique substrate; (3) a chokepoint, because it consumes a unique substrate and produces a unique product.

This Article

  1. Published in Advance April 12, 2004, doi: 10.1101/gr.2050304 Genome Res. 14: 917-924

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