Computational Analysis of Plasmodium falciparum Metabolism: Organizing Genomic Information to Facilitate Drug Discovery

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Figure 1
Figure 1

Both of these reactions are catalyzed by the same protein, MAL6P1.121. Therefore, MAL6P1.121 is associated with two distinct Enzymatic-Reaction frames, each linking the protein to one specific reaction. In this manner, inhibitors can be specified for a particular enzyme/reaction pair instead of for a reaction (which may be catalyzed by numerous enzymes with different inhibitor sensitivities) or for a protein (which may have multiple active sites).

This Article

  1. Genome Res. 14: 917-924

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