Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 4
Figure 4

The power using SNPs with different density with α = 80% and β = 10%. SNPs with minor allele frequency >0.05 are used. The power is obtained using two-locus haplotype data. In each bin (i.e., distance between adjacent markers), it shows the power using (from left to right): (1) all SNPs for block partitioning and tag SNP selection; (2) tag SNPs identified by the haplotype data; (3) the same number of random SNPs as in set 2; (4) tag SNPs identified by the genotype data; (5) the same number of random SNPs as in set 4.

This Article

  1. Genome Res. 14: 908-916

Preprint Server