Systematic Insertional Mutagenesis of a Streptomycete Genome: A Link Between Osmoadaptation and Antibiotic Production

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 3
Figure 3

Antibiotic overproduction by the S. coelicolor osaB mutant AB001. Graphs of yields (the average of three independent experiments; standard deviations were <5% of the plotted values) at indicated time-points of (A) actinorhodin and γ-actinorhodin, and (B) undecylprodigiosin relative to cell density (OD450) produced by submerged cultures grown in liquid R5 with or without 10.3% sucrose (S); (•) AB001 (+S); (▪) M145 (+S); (♦) AB001 (-S); (▴) M145 (-S).

This Article

  1. Published in Advance April 12, 2004, doi: 10.1101/gr.1710304 Genome Res. 14: 893-900

Preprint Server



Current Issue

  1. February 2026, 36 (2)
  1. Current Issue
  1. Alert me to new issues of Genome Research