The Human MitoChip: A High-Throughput Sequencing Microarray for Mitochondrial Mutation Detection

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Figure 2
Figure 2

Analysis of primary tumors and matched body fluid samples (urine or pancreatic juice) obtained from patients with bladder cancer (n=5) and pancreatic cancer (n=4). In each case illustrated, a heteroplasmic mitochondrial mutation identical to one seen in the primary tumor DNA (left hemi-panel) is also found in the fluid DNA (right hemi-panel). The JHU_MITO ID number, type of specimen, the mitochondrial nucleotide position involved, and the specific base change are detailed for each tumor-fluid pair illustrated.

This Article

  1. Genome Res. 14: 812-819

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