Figure 4
FISH confirmation. An example of (a) metaphase and (b) interphase FISH hybridization with a duplicated BAC clone (RP23–3D2; see Table 4) that was identified by the whole-genome shotgun detection strategy. Increased signal intensity was confirmed using (c) cohybridization with a unique probe (RP21-344N12) in the same nucleus as shown in b. Tandem segmental duplications were most frequently observed (Table 4). The results of all FISH experiments are available online (http://www.biologia.uniba.it/mouse/).
