Aligning Multiple Genomic Sequences With the Threaded Blockset Aligner

Table 1.

Average Running Time to Produce a Multiple Alignment of the Given Sequences


Program

Running time, human-mouse-rat (sec)

Running time, nine mammals (sec)
MULTIZ 7.5 NA
TBA 7.7 70.2
TBA (R = 50) 8.3 82.8
CLUSTALW 700.4 3000.9
MLAGAN 31.2 166.8
MAVID 6.7 38.5
DIALIGN 2894.2 35,954.4
DIALIGN/CHAOS
764.4
13,580.7
  • Each sequence is ∼50 kb. The time for masking repeats using Repeat-Masker is not included. Programs were run on 866-MHz Pentium III processors with 1 Gb of memory.

This Article

  1. Genome Res. 14: 708-715

Preprint Server