Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human

Table 1.

Comparison of the Exon-Based Synteny Map and Three-Way Alignments


Length of alignments (bp)

Total number of alignments

Number of alignments overlapping synteny maps

Agreement between methods (%)

Cumulative agreement (%)a

Total size (Mb)

Total size of disagreement (Mb)
>100 8080 7848 97.1 97.1 2243 59.0
50—100 432 301 69.7 95.7 33 9.4
10—50 474 157 33.1 92.4 12 7.3
1—10 613 80 13.1 87.4 1 0.9
   Total
9599
8386
87.4
n.a.
2289
77 (3.4%)
  • a Cumulative numbers show percentage alignments in agreement with the synteny map for a particular range summed up with higher-length ranges, for example 92.4% agreement was achieved for all alignments longer than 10 kb

This Article

  1. Genome Res. 14: 685-692

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