Insertions and Deletions Are Male Biased Too: A Whole-Genome Analysis in Rodents

Table 3.

Nucleotide Substitution Rates Between Mouse and Rat Estimated From the AR Sequences


Data set

NX

LX (bp)

RateX

NA

LA (bp)

RateA

X/A

α (95% Cl)
All ARs 28,091 5,234,761 0.150 ± 0.072 526,062 94,984,067 0.168 ± 0.076 0.897 1.892
Young ARs
1,652
31,508
0.155 ± 0.060
31,969
6,180,668
0.174 ± 0.067
0.895
1.914 (1.651—2.271)
  • NX and NA indicate the number of individual ancestral repeats examined on chromosome X and autosomes, respectively; LX and LA, the lengths of the ARs examined on chromosome X and autosomes, respectively; RateX and RateA, the nucleotide substitution rates (weighted by the length of ARs) and their standard deviations on chromosome X and autosomes, respectively; X/A, the ratio of nucleotide substitution rates on chromosome X versus autosomes; and α (95% Cl), the male-to female mutation rate ratio and its 95% confidence interval (given only for young ARs, as bootstrap procedure for all ARs is very computationally intensive).

This Article

  1. Genome Res. 14: 567-573

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