Occurrence and Consequences of Coding Sequence Insertions and Deletions in Mammalian Genomes

Table 5.

Protein Context of Insertion and Deletion Events




Background (% neighboring residues)

Ins (%)

Del (%)

Total events (%)
Low complexity (Seg) 8.80 28.94 26.40 27.48
Transmembrane 5.13 0.94 0.80 0.86
Coiled coil 2.69 3.10 2.10 2.52
Pfam domain 39.30 12.65 10.10 11.18
Signal peptide
1.00
1.88
1.30
1.54
  • The context of events was measured from annotation of the nonevent sequence (ancestral with respect to the indel). The background measure is the percentage of residues meeting the defined criteria, in the rodent nonredundant protein data set (see Methods).

This Article

  1. Genome Res. 14: 555-566

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