Reconstructing the Genomic Architecture of Ancestral Mammals: Lessons From Human, Mouse, and Rat Genomes

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Figure 1
Figure 1

(A) The 162 two-way synteny blocks between mouse and rat, of size at least 300 kb, computed by direct two-way comparison of mouse and rat. Synteny blocks are shown as rectangles with a diagonal stripe to indicate direction. (B) The 391 three-way human–mouse–rat syntenic blocks of size at least 300 kb, shown in their mouse–rat coordinates. Introducing human splits of many of the synteny blocks in A into smaller ones in B, and also removes regions that do not have a human homolog. Higher quality versions of these plots are available in the Supplemental materials.

This Article

  1. Genome Res. 14: 507-516

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