MCALIGN: Stochastic Alignment of Noncoding DNA Sequences Based on an Evolutionary Model of Sequence Evolution

Table 5.

MC Analysis for Cases of Discrepancy Between the Relative Frequency of Indels in the Simulation Model and MC Analysis Model


θ simulated

Actual t

Observed t (ermse)

Estimated t (ermse)
0.112 0.1 0.107 (0.0263) 0.105 (0.0262)
0.450 0.103 (0.0254) 0.107 (0.0318)
0.112 0.2 0.206 (0.0306) 0.204 (0.0336)
0.450 0.205 (0.0346) 0.245 (0.0716)
0.112 0.3 0.298 (0.0489) 0.288 (0.0462)
0.450

0.295 (0.0490)
0.379 (0.1080)
  • Pairs of sequences were simulated with the value of θ shown (the rate of indels relative to nucleotide substitutions). The value of θ assumed in the MC alignment analysis was 0.225. There were 50 replicates per value simulated.

This Article

  1. Genome Res. 14: 442-450

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