MCALIGN: Stochastic Alignment of Noncoding DNA Sequences Based on an Evolutionary Model of Sequence Evolution

Table 4.

MC Analysis With Simulations of Three-Way Alignments in Which Equal Branch Lengths Are Assumed in MC Analysis


Actual t1,2 and t(1,2)3

Observed t1,2 (ermse)

Estimated t1,2 (ermse)

Observed t(1,2)3 (ermse)

Estimated t(1,2)3 (ermse)
0.05 0.0500 (0.0138) 0.0473 (0.0140) 0.0531 (0.0178) 0.0507 (0.0166)
0.1 0.1017 (0.0282) 0.0976 (0.0277) 0.1006 (0.0211) 0.0955 (0.0208)
0.15 0.1521 (0.0280) 0.1462 (0.0289) 0.1403 (0.0290) 0.1390 (0.0313)
0.2 0.2136 (0.0340) 0.2055 (0.0349) 0.1797 (0.0381) 0.1742 (0.0460)
0.25 0.2757 (0.0519) 0.2672 (0.0540) 0.2258 (0.0371) 0.2109 (0.0538)
0.3
0.3068 (0.0412)
0.2984 (0.0510)
0.2520 (0.0546)
0.2600 (0.0599)
  • The internal and external branch lengths are equal (i.e., t1,2 and t(1,2)3), and alignment probability is evaluated under this model.

This Article

  1. Genome Res. 14: 442-450

Preprint Server