Table 4.
Replication of Linkage Region in a Family With a Combination of Chronic Mucocutaneous–Candidiasis and Thyroid Disease, Using SNPs
|
|
Informative markers on Chr 2 |
LOD score |
P-value |
Interval |
|---|---|---|---|---|
| 10 cM STR genome scan | 28 | 4.21 | 0.0039 | 35.28 cM |
| SNP array (11,555 SNPs)
|
525
|
8.39
|
0.0078
|
17.73 cM
|
-
Nonparametric LOD (NPL) scores were calculated using GENEHUNTER on the 28 STR markers and 525 SNPs on chromosome 2.
