Tracking the Evolution of the SARS Coronavirus Using High-Throughput, High-Density Resequencing Arrays

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Figure 4
Figure 4

Effects of secondary structure on probe annealing and ambiguous calls. The most stable structure as predicted using GeneRunner software, is illustrated for two sequences with recurrent Ns; (A) bases 25953–25959, (B) bases 22781–22796. In both cases, the frequency of ambiguous calls peaks at the bases within the predicted loop structure.

This Article

  1. Genome Res. 14: 398-405

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