Figure 1
SARS Resequencing array. (A) Diagram of the different sequence variants that can be detected by the array. Specific probes were designed to screen for previously published insertion and deletion sequences. (B) Resequencing array hybridized with Cy-3-labeledSARS-CoV cDNA. (C) Close-up view of oligonucleotide probes synthesized on the array. The four possible nucleotides for each position are synthesized adjacent to each other. SARS cDNA bound to perfect-match (PM) probes (in red) fluoresce with higher intensity than those bound to mismatch (MM) probes (in black).
