Table 2.
Fraction of Functional Modules More Than Two Standard Deviations Modular Than Random
|
|
No data filter by cross-comparison |
Data filter by cross-comparison |
||||
|---|---|---|---|---|---|---|
| No paralogy filter |
Random shuffling |
Random sampling |
Random shuffling |
Random sampling |
||
| Known complexes in yeast | 0.89 | 0.54 | 0.91 | 0.56 | ||
| TAP protein complexes | 0.58 | 0.17 | 0.63 | 0.22 | ||
| HMS-PCI protein complexes | 0.64 | 0.17 | 0.71 | 0.25 | ||
| Genes sharing TFBS | 0.61 | 0.25 | 0.67 | 0.28 | ||
| Transcriptional clusters | 0.30 | 0.00 | 0.37 | 0.01 | ||
| Predicted regulons in E. coli | 0.91 | 0.05 | 0.95 | 0.41 | ||
| Known operons in E. Coli | 0.95 | 0.68 | 0.97 | 0.73 | ||
| EcoCyc metabolic pathways | 0.93 | 0.50 | 0.97 | 0.59 | ||
| KEGG maps
|
0.48
|
0.03
|
0.85
|
0.13
|
||
| Paralogy filter
|
Random shuffling
|
Random sampling
|
Random shuffling
|
Random sampling
|
||
| Known complexes in yeast | 0.95 | 0.68 | 0.94 | 0.69 | ||
| TAP protein complexes | 0.67 | 0.37 | 0.74 | 0.43 | ||
| HMS-PCI protein complexes | 0.66 | 0.35 | 0.80 | 0.38 | ||
| Genes sharing TFBS | 0.72 | 0.28 | 0.72 | 0.40 | ||
| Transcriptional clusters | 0.60 | 0.14 | 0.67 | 0.13 | ||
| Predicted regulons in E. coli | 0.95 | 0.20 | 0.97 | 0.67 | ||
| Known operons in E. coli | 1.00 | 0.91 | 0.97 | 0.92 | ||
| EcoCyc metabolic pathways | 0.98 | 0.71 | 1.00 | 0.74 | ||
| KEGG maps
|
0.60
|
0.17
|
0.88
|
0.35
|
||
