
(A) A schematic demonstration of the construction of a domain graph. Four domains (a, b, c, and d) are present in two given proteins. As a result, a domain graph with four vertices and four edges is formed. The vertices represent the domains with the same color. (B) The process of Comparative Analysis of Protein Domain Organization (CADO). Two domain graphs are shown in blue and pink (top) and their common organization is shown in brown in the bottom.











